Product Type
Oral broad-spectrum anthelmintic tablets for the prevention of heartworm
disease and the control of roundworms, hookworms and whipworms in dogs.
Description and Composition
Oral tablets of 4 strengths are available:
- INTERCEPTOR 2.3mg, a tablet containing 2.3 mg of milbemycin oxime.
- INTERCEPTOR 5.75mg, a tablet containing 5.75 mg of milbemycin oxime.
- INTERCEPTOR 11.5mg, a tablet containing 11.5 mg of milbemycin oxime.
- INTERCEPTOR 23mg, a tablet containing 23 mg of milbemycin oxime.
Properties
Milbemycin oxime, the active ingredient, is a mixture of the macrolides
milbemycin A3 oxime and milbemycin A4 oxime. It interacts with the GABA
receptors of the nervous system like other macrolides leading to paralysis.
Milbemycin oxime is active against nematodes and arthropods.
INTERCEPTOR is well tolerated by dogs of all ages and breeds, including
Collie breeds and breeding animals.
Interactions with other medicines are not known.
Indications
INTERCEPTOR is indicated for the prevention of heartworm (Dirofilaria
immitis) disease and the treatment and control of roundworms (Toxocara canis,
Toxascaris leonina), hookworms (Ancylostoma caninum) and whipworms (Trichuris
vulpis) in dogs.
Dosage and Administration
INTERCEPTOR is given orally at the minimum dose of 0.5 mg milbemycin oxime
per kg body weight according to the following table:
| Weight of dog |
Tablets |
| 1 to 4 kg |
1 tablet of INTERCEPTOR 2.3mg |
| >4 to 11 kg |
1 tablet of INTERCEPTOR 5.75mg |
| >11 to 23 kg |
1 tablet of INTERCEPTOR 11.5mg |
| >23 to 45 kg |
1 tablet of INTERCEPTOR 23mg |
Dogs over 45 kg are given an appropriate combination of tablets.
INTERCEPTOR must be given at monthly intervals, preferably on the same date
starting within 1 month of the begin of the transmission season and continuing
until 1 dose after its end. Where heartworm transmission is not seasonal
INTERCEPTOR is given throughout the year. Dogs living in heartworm-free regions
and travelling to heartworm risk areas should be treated within 1 month of the
beginning of the exposure to transmission. If necessary administrations should
be repeated monthly until 1 administration after the end of the exposure risk.
If INTERCEPTOR replaces another heartworm prevention the first dose should be
given within 1 month after the previous treatment. The tablets can be given
directly into the mouth of the dog or they can be given in a portion of food.
Special Precautions and Warnings
Dogs should be tested for heartworm infection. Heartworm prevention programs
should be started only in dogs found to be uninfected.
Formulations and Packages
There are 4 tablet strengths in color-coded packs:
- INTERCEPTOR containing 2.3 mg milbemycin oxime, in brown packs.
- INTERCEPTOR containing 5.75 mg milbemycin oxime, in green packs.
- INTERCEPTOR containing 11.5 mg milbemycin oxime, in yellow packs.
- INTERCEPTOR containing 23 mg milbemycin oxime, in white packs.
All 4 tablet sizes are available in 6 and 12 packs:
- One carton box with 1 card containing 6 blistered tablets.
- Two carton boxes with each card containing 6 blistered tablets.
Storage Recommendations and Shelf Life
The shelf life of INTERCEPTOR is 3 years when stored below 30°C.
INTERCEPTOR by Novartis of Switzerland
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